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In the absence of genetic testing, persons who are at increased risk for HNPCC by virtue suburban housewife of their family history also are advised to follow the same cancer screening guidelines as mutation carriers. As part of a longitudinal study of psychosocial aspects of HNPCC genetic counseling and testing, we evaluated colonoscopy utilization before and after genetic testing. Subjects were 79 adults from families with a known HNPCC-predisposing mutation and with no suburban housewife prior history of CRC. Prior to genetic counseling, 53% (n=42) had ever had suburban housewife a colonoscopy.  After genetic testing, 33% (n=26) were positive for an HNPCC-predisposing mutation. There was no difference in baseline prevalence of colonoscopy use between mutation carriers and non-carriers (50% and 54%, respectively). Within 6 months of receiving test results, 76% of mutation carriers reported that they had undergone colonoscopy since receiving their results, a significantly greater proportion compared with baseline utilization and with noncarriers (F=18.87,
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