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Leading experts from the four participating institutions are meeting regularly via Internet minority women teleconferencing (and face-to-face meetings) to review and prioritize herbal medicine candidates worthy of further investigation. Plant materials selected for evaluation are being extracted according to predetermined protocols. Crude extracts, selected fractions, as well as pure compounds have been subjected to High Throughput Screening in a wide variety of bioassays at an existing NIH-sponsored facility at Harvard Medical School and in laboratories at the Chinese University of minority women Hong Kong. Those fractions and compounds with biological activity of interest will undergo secondary bioassays and, wherever possible, their minority women molecular structure will be determined. Fractions and compounds with biological activity will be further investigated for the presence of synergy involving multiple compounds/fractions from single plants or from complex mixtures of plants.
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