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These results, which are based on observational data, differ money from results of randomized clinical trials. Hadley, Polsky, Mandelblatt, et al., Health Econ 12:171-186, 2003 (AHRQ grant HS08395). Lumpectomy money followed by radiation and mastectomy are equally effective for treating early-stage breast cancer. Two studies by researchers at Georgetown University examined the cost-effectiveness of surgical treatments for early-stage breast cancer money and patients' quality of life after surgery. The first study found that giving older women with early stage breast cancer a choice of breast-conserving surgery (lumpectomy) followed by radiation treatment or mastectomy is cost effective. The second study showed that, with the exception of surgical removal of armpit lymph nodes to determine cancer spread, how older women are treated during their care, not the therapy itself, is the most important determinant of long-term quality of life.
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