Grant Holder(s) Dr D boomers scoreboard
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Grant Holder(s) Dr D Riccardi PhD Institute Cardiff School of Biosciences Cardiff University CARDIFF Title of Research scoreboard Role of a calcium receptor in the function of bone cells Summary of Research Osteoporosis is a disease which affects four out scoreboard of ten women over 50 and is characterised by a reduced bone mass scoreboard due to an imbalance between breakdown and formation of bone. Despite such a widespread problem, there is a dearth of information on how bone formation and resorption are controlled and therefore pharmacological therapy is only partly effective. Calcium is the major constituent of bone and changes in blood calcium levels can directly regulate bone metabolism. Recently we have identified a cell-associated protein which senses changes in the amounts of calcium in the blood. Alterations in the function of this protein in humans severely affects bone integrity and causes conditions ranging from illness to death as a result of a deficiency or an excess of calcium.
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